| Product Name: | LGD-4033 |
| Synonyms: | 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile(LGD-4033);LGD-4033;4-[(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrile;4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile;LIGANDROL;4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile;lgd 4033 sarms powder lgd-4033 ligandrol;POWDER LGD-4033 LIGANDROL |
| CAS: | 1165910-22-4 |
| MF: | C14H12F6N2O |
| MW: | 338.25 |
| EINECS: | 1806241-263-5 |
| Product Categories: | LGD-4033 whatsapp;SARMs(Selective androgen receptor modulator);1165910-22-4 |
| Mol File: | 1165910-22-4.mol |
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| LGD-4033 Chemical Properties |
| Melting point | 108 - 111°C |
| Boiling point | 439.9±45.0 °C(Predicted) |
| density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Acetone (Slightly), Chloroform (Slightly, Heated), Methanol (Slightly) |
| form | A crystalline solid |
| pka | 12.06±0.20(Predicted) |
| color | White to Pale Beige |
| Stability: | Hygroscopic |
| InChI | InChI=1S/C14H12F6N2O/c15-13(16,17)10-6-9(4-3-8(10)7-21)22-5-1-2-11(22)12(23)14(18,19)20/h3-4,6,11-12,23H,1-2,5H2/t11-,12-/m1/s1 |
| InChIKey | OPSIVAKKLQRWKC-VXGBXAGGSA-N |
| SMILES | C(#N)C1=CC=C(N2CCC[C@@H]2[C@@H](O)C(F)(F)F)C=C1C(F)(F)F |
| LGD-4033 Usage And Synthesis |
| Description | LGD-4033 is a Selective Androgen Receptor Modulator (SARM). SARMs are a class of non-steroidal anabolic agents that bind androgen receptors with high affinity. LGD-4033 has been shown to provide benefits similar to traditional anabolic agents, (e.g., increased muscle mass, fat loss, and improved bone density) but with far fewer side effects (e.g., oily skin, acne, over-conversion to estrogen, etc.). Both men and women may also appreciate improved libido. All of these benefits are achieved without increasing androgen levels. Its anabolic effects are roughly the same or greater than testosterone, even at low doses. Some prescribers will recommend a trial of SARMs for low testosterone levels prior to utilizing testosterone replacement therapy. |
| Uses | Ligandrol, also known as LGD-4033, is a nonsteroidal oral drug used for the treatment of muscle wasting and osteoporosis in healthy young men. |
| Biological Activity | LGD-4033 is a potent nonsteroidal selective androgen receptor modulator (SARM) that binds to the androgen receptor with a Ki value of 1 nM. In animal models, LGD-4033 displays robust selectivity for muscle versus prostate tissues, anabolic activity in the muscle, and anti-resorptive and anabolic activity in bone. LGD 4033 has been abused as a performance-enhancing drug and the identification of its in vitro metabolites has been described. This product is intended for research and forensic applications. |
