• CHRP-6
  • CHRP-6

CHRP-6

No.CAS:136054-22-3
GHRP6 This PRODUCTS ARE INTENDED FOR RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.
$5.00
Purity:
99%
Content::
2mg 5mg 10mg
Form:
Lyophilized powder
Transportation:
Door to door
  • CHRP-6

SPECIFICATION

H-HIS-D-TRP-D-LYS-TRP-D-PHE-LYS-NH2 Basic information
Product Name: H-HIS-D-TRP-D-LYS-TRP-D-PHE-LYS-NH2
Synonyms: [D-TRP7, D-LYS8, D-PHE10]-ALPHA-MELANOCYTE STIMULATING HORMONE (6-11) AMIDE;(D-TRP7,D-LYS8,D-PHE10)-ALPHA-MSH (6-11) AMIDE;[D-LYS3]-GHRP-6;[D-LYS3]-GHRP-6 [HIS1, D-LYS3, LYS6]-GHRP HIS-D-TRP-D-LYS-TRP-D-PHE-LYS-NH2;[D-LYS3]-GROWTH HORMONE RELEASING PEPTIDE;(D-LYS3)-GROWTH HORMONE-RELEASING PEPTIDE-6;HWKWFK-NH2;[HIS1, D-LYS3, LYS6]-GHRP
CAS: 136054-22-3
MF: C49H63N13O6
MW: 930.11
EINECS:
Product Categories: peptide;Ghrelin receptor;Peptides
Mol File: 136054-22-3.mol
H-HIS-D-TRP-D-LYS-TRP-D-PHE-LYS-NH2 Structure
H-HIS-D-TRP-D-LYS-TRP-D-PHE-LYS-NH2 Chemical Properties
Boiling point  1422.5±65.0 °C(Predicted)
density  1.314±0.06 g/cm3(Predicted)
storage temp.  −20°C
solubility  Soluble to 0.50 mg/ml in H2O
form  lyophilized powder
pka 13.37±0.46(Predicted)
Water Solubility  Soluble in water.
Stability: Hygroscopic

H-HIS-D-TRP-D-LYS-TRP-D-PHE-LYS-NH2 Usage And Synthesis
Uses [D-Lys3]-GHRP6 has been used-
  • to treat bovine somatotropes to determine the release of GH from treated cells and non-treated or control cells
  • for intraperitoneal injection to groups of broiler chicken to determine the effect on feed intake, weight gain, and feed conversion ratio
Biochem/physiol Actions [D-Lys3]-GHRP6 (growth hormone releasing peptide 6) induces the secretion of growth hormone (GH). In the membrane of clonal GC somatotropes, this peptide elevates the number of functional voltage-gated Ca2+ and Na+ channels. Chronic treatment with this peptide causes an elevation in Na+ macroscopic current in bovine pituitary somatotropes in culture, which results in an increase in the release of GH.
IC 50 0.9 μm
storage Desiccate at -20°C
references [1]. schith hb, muceniece r, wikberg je. characterization of the binding of msh-b, hb-228, ghrp-6 and 153n-6 to the human melanocortin receptor subtypes. neuropeptides. 1997 dec;31(6):565-71.
[2]. traebert m, riediger t, whitebread s, scharrer e, schmid ha. ghrelin acts on leptin-responsive neurones in the rat arcuate nucleus. j neuroendocrinol. 2002 jul;14(7):580-6.
[3]. pinilla l, barreiro ml, tena-sempere m, aguilar e.role of ghrelin in the control of growth hormone secretion in prepubertal rats: interactions with excitatory amino acids. neuroendocrinology. 2003 feb;77(2):83-90.