• MT1
  • MT1

MT1 (Melanotan I)

No.CAS: 75921-69-6
Melanotan 1 This PRODUCTS ARE INTENDED FOR RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.
$5.00
Purity:
99%
Content:
10mg
Form:
Lyophilized powder
Transportation:
Door to door
  • MT1

SPECIFICATION

Melanotan 1 Basic information
Features
Product Name: Melanotan 1
Synonyms: [NLE4,D-PHE]ALPHA-MELANOCYTE STIMULATING HORMONE;(NLE4,D-PHE7)-ALPHA-MSH;[Nle4,D-Phe7]α-MSH;Ac-L-Ser-L-Tyr-L-Ser-L-Nle-L-Glu-L-His-D-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2;N-Ac-L-Ser-L-Tyr-L-Ser-L-Nle-L-Glu-L-His-D-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2;[Nle4,DPhe7] a-MSH, amide;[Nle4,DPhe7] a-MSH, amide:Melanotan Ⅰ;[Nle4, D-Phe7]-α-MSH, amide
CAS: 75921-69-6
MF: C78H111N21O19
MW: 1646.85
EINECS: 211-519-9
Mol File: 75921-69-6.mol
Melanotan 1 Structure
Melanotan 1 Chemical Properties
density  1.46±0.1 g/cm3(Predicted)
RTECS  OS1830200
storage temp.  −20°C
form  Solid
pka 4.43±0.10(Predicted)
Water Solubility  Soluble to 0.60 mg/ml in sterile water
InChIKey UAHFGYDRQSXQEB-LEBBXHLNSA-N
CAS DataBase Reference 75921-69-6(CAS DataBase Reference)
Melanotan 1 Usage And Synthesis
Features Afamelanotide is a potent, linear synthetic analog of the naturally occurring peptide hormone α-melanocyte-stimulating hormone (α-MSH).Modified to have a stronger binding affinity to melanocortin- 1 receptor (MC1R) and a smaller disassociation constant, afamelanotide has a longer half-life and subsequently exerts longer pharmacologic activity than its parent hormone.
Uses Melanotan 1 is a highly potent melanotropin with extended biological activity and resistance to enzymatic degredation by serum enzymes. [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt has been used to detect its effect on O2 consumption and CO2 production in C57BL/6 mice. It is also used to determine its effect on leptin secretion in the primary cultures of differentiated adipocytes.
Definition ChEBI: Afamelanotide is a polypeptide comprising of 13 amino acids which is an analogue of alpha-melanocyte stimulating hormone. It is approved as a dermatologic drug for the prevention of phototoxicity in adult patients with erythropoietic protoporphyria. It has a role as a dermatologic drug.
General Description [Nle4, D-Phe7]-α-melanocyte stimulating hormone is a potent analogue of α;-melanocyte-stimulating hormone (α -MSH). αMSH is a tridecapeptide, mostly produced by the cells in the brain, pituitary and in circulation.