| Octreotide Information |
| Product Name: | Octreotide |
| Synonyms: | SANDOSTATIN;SMS-201-995;[r-(r*,r*)]-d-phenylalanyl-l-cysteinyl-l-phenylalanyl-d-tryptophyl-l-lysyl-l-threonyl-n-[2-hydroxy-1-(hydroxy-methyl)propyl]-cysteinamide cyclic(2->7)-disulfide;OCTREOTIDE;OCTREOTIDE (SMS 201-995), ACETATE;cyclic(2-7)-disulfide,(r-l-threonyl-n-(2-hydroxy-1-(hydroxymethyl)propyl);Octreotide (D-Phe5,Cys6·11,D-Trp8,L-Threoninol12)-SoMatostatin-14 (5-12), SMS-201-995;D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxyMethyl)propyl]- |
| CAS: | 79517-01-4 |
| MF: | C51H70N10O12S2 |
| MW: | 1079.3 |
| EINECS: | 616-695-4 |
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| Octreotide Chemical Properties |
| Melting point | 153-156°C |
| Alpha | D20 -42° (c = 0.5 in 95% acetic acid) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: soluble |
| Form | Solid |
| Color | White to Off-White |
| CAS DataBase Reference | 79517-01-4 |
| Octreotide Usage And Synthesis |
Storage properties |
cold warehouse, ventilated and dry; and separately stored with food raw materials |
Extinguishing media |
water, carbon dioxide, dry power, sandy soil |
Chemical Properties |
Colourless to off-white lyophilised solid |
| Originator |
Sandostatin,Novartis Pharma AG,Switz. |
Uses |
> Octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly > Octreotide acetate USP (Sandostatin) is used to treat Mestastatic carcinoid tumors; vasoactive intestinal peptide-secretory tumors. > natural hormone somatostatin |
Therapeutic Function |
Antiulcer, Growth hormone inhibitor |
General Description |
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Clinical Use |
Relief of symptoms of gastro-enteropancreatic endocrine tumours and acromegaly |
