| TRH Information |
| Product Name: | TRH |
| Synonyms: | THR 1-2;THR 2-3;PROTIRELIN;PYROGLU-HIS-PRO AMIDE;PYROGLU-HIS-PRO NH2;PYR-HIS-PRO-NH2(TRH);PYR-HIS-PRO-NH2;PGLU-HIS-PRO-NH2 |
| CAS: | 24305-27-9 |
| MF: | C16H22N6O4 |
| MW: | 362.38 |
| EINECS: | 246-143-4 |
| Product Categories: | Peptide;THYPINONE |
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| TRH Chemical Properties |
| Boiling point | 494°C (rough estimate) |
| Density | 1.1675 (rough estimate) |
| Refractive index | 1.6000 (estimate) |
| Storage temp. | −20°C |
| Solubility | H2O: 10 mg/mL, clear, colorless |
| Pka | 13.05±0.20(Predicted) |
| Form | powder |
| color | White to Off-White |
| PH | pH (10g/l, 25℃) : 3.0～4.0 |
| Merck | 13,9663 |
| BRN | 770238 |
| Stability: | Hygroscopic |
| TRH Usage And Synthesis |
General Description |
Thyrotropin releasing hormone (TRH) is a tripeptide hypothalamic regulatory hormone, encoded by the gene mapped to human chromosome 3q13.3-q21. TRH is expressed in a variety of organs including central nervous system (CNS) and gastrointestinal tract. |
Chemical Properties |
White or yellowish-white powder, hygroscopic. |
Uses |
Thyrotropin-Releasing Hormone is a hypothalamic hypophysiotropic neuropeptide, which has the ability to stimulate the release of thyroid-stimulating hormone in mammals. It is proven that Thyrotropin-Releasing Hormone can be used to accelerate wound healing. |
Definition |
ChEBI: Protirelin is a tripeptide composed of L-pyroglutamyl, L-histidyl and L-prolinamide residues joined in sequence. It has a role as a human metabolite. It is a peptide hormone and a tripeptide. |
Indications |
Thyrotropin-releasing hormone, or protirelin, consists of three amino acids. TRH (Relefact TRH) is used for tests to distinguish primary from secondary hypothyroidism. |
